Jean-Pierre Bronowicki Selected Research

N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamide

9/2015	Early virological assessment during telaprevir- or boceprevir-based triple therapy in hepatitis C cirrhotic patients who failed a previous interferon based regimen - The ANRS CO20-CUPIC study.
1/2015	Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study.
7/2014	Effectiveness of telaprevir or boceprevir in treatment-experienced patients with HCV genotype 1 infection and cirrhosis.
5/2014	Boceprevir plus peginterferon α-2b/ribavirin in chronic hepatitis C genotype 1: impact of baseline viral load on sustained virologic response.
5/2014	Overall safety profile of boceprevir plus peginterferon alfa-2b and ribavirin in patients with chronic hepatitis C genotype 1: a combined analysis of 3 phase 2/3 clinical trials.
4/2014	Boceprevir for chronic HCV genotype 1 infection in patients with prior treatment failure to peginterferon/ribavirin, including prior null response.
4/2013	Boceprevir for previously untreated patients with chronic hepatitis C Genotype 1 infection: a US-based cost-effectiveness modeling study.
3/2013	Anemia during treatment with peginterferon Alfa-2b/ribavirin and boceprevir: Analysis from the serine protease inhibitor therapy 2 (SPRINT-2) trial.
11/2012	Protease inhibitor-based triple therapy in chronic hepatitis C: guidelines by the French Association for the Study of the Liver.
9/2012	Factors that predict response of patients with hepatitis C virus infection to boceprevir.

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Jean-Pierre Bronowicki Research Topics

Disease

42	Fibrosis (Cirrhosis) 06/2022 - 04/2002
40	Infections 10/2020 - 07/2002
32	Chronic Hepatitis C 06/2022 - 02/2006
25	Hepatocellular Carcinoma (Hepatoma) 06/2022 - 08/2003
14	Neoplasms (Cancer) 06/2021 - 12/2006
10	Hepatitis C 01/2022 - 10/2006
7	Liver Neoplasms (Liver Cancer) 06/2021 - 08/2003
6	Liver Diseases (Liver Disease) 01/2022 - 02/2013
5	Carcinogenesis 01/2022 - 08/2003
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2020 - 05/2002
4	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 02/2015
4	Ascites 01/2022 - 02/2006
4	Disease Progression 01/2022 - 09/2015
4	Hypertension (High Blood Pressure) 01/2021 - 01/2017
4	Inflammation (Inflammations) 10/2020 - 11/2016
4	Peritonitis 01/2019 - 03/2006
4	Anemia 01/2015 - 04/2009
4	Crohn Disease (Crohn's Disease) 06/2012 - 11/2006
4	Hyperhomocysteinemia 02/2008 - 06/2005
3	Chronic Hepatitis B 01/2021 - 07/2004
3	Asthenia 10/2020 - 01/2013
3	Fatigue 10/2020 - 01/2017
3	Hepatitis B 12/2019 - 10/2006
3	Coinfection 01/2019 - 07/2004
3	Neutropenia 01/2019 - 02/2013
3	Persistent Infection 01/2017 - 04/2009
3	Malnutrition (Nutritional Deficiencies) 06/2012 - 06/2005
2	Esophageal and Gastric Varices (Esophageal Varices) 06/2022 - 01/2019
2	Hepatorenal Syndrome 01/2022 - 04/2002
2	Thrombosis (Thrombus) 01/2022 - 05/2007
2	Portal Hypertension 01/2022 - 02/2013
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 11/2016
2	Neoplasm Metastasis (Metastasis) 12/2020 - 04/2005
2	Non-alcoholic Fatty Liver Disease 10/2020 - 01/2018
2	Hepatitis 10/2020 - 11/2016
2	Colitis 10/2020 - 08/2008
2	Sclerosing Cholangitis 09/2019 - 11/2006
2	End Stage Liver Disease 04/2019 - 01/2019
2	Thrombocytopenia (Thrombopenia) 01/2019 - 03/2006
2	Liver Failure 01/2017 - 07/2004
2	Fatty Liver 11/2016 - 08/2012
2	Hyperbilirubinemia 06/2015 - 03/2006
2	Virus Diseases (Viral Diseases) 02/2015 - 09/2011
2	Pruritus (Itching) 01/2013 - 04/2009
2	Exanthema (Rash) 01/2013 - 04/2009
2	Body Weight (Weight, Body) 06/2010 - 04/2009

Drug/Important Bio-Agent (IBA)

38	Ribavirin (Virazole)FDA LinkGeneric 10/2020 - 07/2002
21	Antiviral Agents (Antivirals)IBA 06/2022 - 07/2002
18	InterferonsIBA 04/2019 - 07/2002
12	Sorafenib (BAY 43-9006)FDA Link 02/2021 - 09/2015
12	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 09/2015 - 03/2011
11	Protease Inhibitors (Protease Inhibitor)IBA 04/2019 - 12/2011
10	Folic Acid (Vitamin M)FDA LinkGeneric 10/2020 - 01/2003
8	daclatasvirIBA 10/2020 - 09/2012
7	BilirubinIBA 06/2022 - 02/2013
7	AlbuminsIBA 06/2022 - 02/2006
7	RNA (Ribonucleic Acid)IBA 03/2015 - 07/2002
6	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 10/2020 - 08/2003
6	telaprevirIBA 09/2015 - 04/2009
6	faldaprevirIBA 02/2015 - 12/2011
6	deleobuvirIBA 02/2015 - 12/2011
5	peginterferon alfa-2a (Pegasys)FDA Link 06/2013 - 10/2006
5	HomocysteineIBA 08/2008 - 06/2005
4	alpha-Fetoproteins (alpha-Fetoprotein)IBA 06/2021 - 11/2019
4	Biomarkers (Surrogate Marker)IBA 11/2020 - 07/2015
4	SofosbuvirIBA 10/2020 - 01/2016
4	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2019 - 06/2010
4	asunaprevirIBA 05/2015 - 01/2013
4	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 08/2008 - 06/2005
3	Pharmaceutical PreparationsIBA 01/2019 - 01/2017
3	VaccinesIBA 01/2019 - 09/2011
3	Proteins (Proteins, Gene)FDA Link 12/2018 - 02/2012
3	sofosbuvir drug combination ledipasvirIBA 12/2016 - 04/2015
2	Pravastatin (Pravachol)FDA LinkGeneric 02/2021 - 01/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 07/2004
2	SirtuinsIBA 12/2020 - 12/2017
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2020 - 08/2012
2	grazoprevirIBA 01/2020 - 03/2015
2	elbasvirIBA 01/2020 - 03/2015
2	Biological ProductsIBA 04/2019 - 03/2006
2	SimeprevirIBA 04/2019 - 02/2016
2	C-Reactive ProteinIBA 01/2019 - 06/2012
2	CollagenIBA 01/2018 - 11/2016
2	CreatinineIBA 12/2017 - 03/2013
2	NucleosidesIBA 01/2015 - 07/2004
2	peginterferon alfa-2b (Pegintron)FDA Link 05/2014 - 03/2013
2	Erythropoietin FDA Link 09/2013 - 03/2013
2	VitaminsIBA 02/2012 - 06/2005
2	Choline (Choline Chloride)IBA 02/2012 - 08/2003
2	Betaine-Homocysteine S-Methyltransferase (Betaine Homocysteine Methyltransferase)IBA 02/2012 - 08/2007
2	5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase (Methyltetrahydrofolate Homocysteine Methyltransferase)IBA 08/2008 - 08/2007
2	EnzymesIBA 08/2007 - 06/2005
2	Cystathionine beta-Synthase (Serine Sulfhydrase)IBA 08/2007 - 06/2005
2	Interferon-alpha (Interferon Alfa)IBA 10/2006 - 07/2002

Therapy/Procedure

42	Therapeutics 01/2021 - 07/2004
9	Liver Transplantation 01/2022 - 04/2005
4	Aftercare (After-Treatment) 06/2022 - 07/2002
3	Radiotherapy 12/2020 - 05/2015
2	Duration of Therapy 03/2015 - 04/2013
2	Drug Tapering 03/2013 - 03/2011